The novel coronavirus is constantly changing, with new variants forming and spreading across the globe. These variants, called Variants of Concern (VOCs), may be more transmissible, cause more severe disease, or be resistant to current treatments, and thus require special attention. Scientists are studying the genetic changes that occur in VOCs, which are known as mutations, to help inform public health decisions. By studying the mutations that occur in VOCs, scientists gain insight into the virus's behavior and the potential implications of these changes. This knowledge helps healthcare professionals and policy makers make decisions to protect public health.